Human GDF2 (Growth/Differentiation Factor 2) Antibody Pair (STJAP00141)

SPECIFICATIONS
ClonalityMonoclonal/Polyclonal
HostMouse/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human GDF2 protein.
Detection Immunogen: Recombinant Human GDF2 protein.
STJAP00141-50
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General Information

Short DescriptionThis GDF2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
ApplicationsELISA
HostMouse/Goat
ReactivityHuman
NoteFOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Product Properties

ClonalityMonoclonal/Polyclonal
ConjugationUnconjugated/Biotin
Concentration0.5 mg/mL
PurificationCapture Purification: Protein A or G.
Detection Purification: Antigen Affinity.
FormulationCapture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Storage InstructionStore at-20°C for the long term, and avoid freeze-thaw cycles.

Target Information

Gene SymbolGDF2
Gene ID2658
Uniprot IDGDF2_HUMAN
ImmunogenCapture immunogen: Recombinant Human GDF2 protein.
Detection Immunogen: Recombinant Human GDF2 protein.

Additional Info

Post Translational Modifications A reversible disulfide bond can be formed between the two subunits in the homodimer.this has no effect on GDF2 activity.
Function Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Protein Name Growth/Differentiation Factor 2
Gdf-2
Bone Morphogenetic Protein 9
Bmp-9
Database Links Reactome: R-HSA-201451
Cellular Localisation Secreted
Alternative Antibody Pair Names Growth/Differentiation Factor 2 antibody pair
Gdf-2 antibody pair
Bone Morphogenetic Protein 9 antibody pair
Bmp-9 antibody pair
GDF2 antibody pair
BMP9 antibody pair

Information sourced from Uniprot.org

Citations

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