Human GCHFR protein (Recombinant) (His-Tag) (STJP018834)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GCHFR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCHFR |
| Gene ID | 2644 |
| Uniprot ID | GFRP_HUMAN |
| Accession Number | NP_005249 |
| Immunogen | Human |
| Immunogen Region | 1-84aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPYLLIS TQIRMEVGPT MVGDEQSDPE LMQHLGASKR RALGNNFYEY YVDDPPRIVL DKLERRGFRV LSMTGVGQTL VWCLHKE |
Additional Info
| Tissue Specificity | In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). |
| Function | Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine. |
| Protein Name | Gtp Cyclohydrolase 1 Feedback Regulatory ProteinGfrpGtp Cyclohydrolase I Feedback Regulatory ProteinP35 |
| Database Links | Reactome: R-HSA-1474151 |
| Cellular Localisation | NucleusNucleus MembraneCytoplasmCytosol |
| Alternative Protein Names | Gtp Cyclohydrolase 1 Feedback Regulatory Protein proteinGfrp proteinGtp Cyclohydrolase I Feedback Regulatory Protein proteinP35 proteinGCHFR proteinGFRP protein |
Information sourced from Uniprot.org