Human GCDH protein (Recombinant) (His-Tag) (STJP016762)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GCDH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 5mM DTT, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCDH |
| Gene ID | 2639 |
| Uniprot ID | GCDH_HUMAN |
| Accession Number | NP_000150 |
| Immunogen | Human |
| Immunogen Region | 45-438aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform Long and isoform Short are expressed in fibroblasts and liver. |
| Function | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. |
| Protein Name | Glutaryl-Coa Dehydrogenase - MitochondrialGcd |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Glutaryl-Coa Dehydrogenase - Mitochondrial proteinGcd proteinGCDH protein |
Information sourced from Uniprot.org