Human GCA protein (Recombinant) (His-Tag) (STJP017024)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GCA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCA |
| Gene ID | 25801 |
| Uniprot ID | GRAN_HUMAN |
| Accession Number | NP_036330.1 |
| Immunogen | Human |
| Immunogen Region | 1-217aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow. |
| Function | Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions. |
| Protein Name | Grancalcin |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmCytoplasmic Granule MembranePeripheral Membrane ProteinCytoplasmic SidePrimarily Cytosolic In The Absence Of Calcium Or Magnesium IonsRelocates To Granules And Other Membranes In Response To Elevated Calcium And Magnesium Levels |
| Alternative Protein Names | Grancalcin proteinGCA proteinGCL protein |
Information sourced from Uniprot.org