| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GBP4-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GBP4 |
| Gene ID: | 115361 |
| Uniprot ID: | GBP4_HUMAN |
| Immunogen Region: | Met1-Lys292 |
| Immunogen: | Homo sapiens (Human) |
| Function | Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens. Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor. |
| Protein Name | Guanylate-Binding Protein 4Gtp-Binding Protein 4Gbp-4Guanine Nucleotide-Binding Protein 4 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | Golgi Apparatus MembraneCytoplasmNucleusPerinuclear RegionHeterodimers With Gbp1Gbp2 And Gbp5 Localize In The Compartment Of The Prenylated Gbps: With Gbp1 In A Vesicle-Like CompartmentWith Gbp2Around The Nucleus And With Gbp5At The Golgi Apparatus |
| Alternative Protein Names | Guanylate-Binding Protein 4 proteinGtp-Binding Protein 4 proteinGbp-4 proteinGuanine Nucleotide-Binding Protein 4 proteinGBP4 protein |
Information sourced from Uniprot.org