Human GAS2 protein (Recombinant) (N-His) (STJP003298)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GAS2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | GAS2 |
| Gene ID | 2620 |
| Uniprot ID | GAS2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly64-Asp267 |
Additional Info
| Post Translational Modifications | Cleaved, during apoptosis, on a specific aspartic residue by caspases. Phosphorylated on serine residues during the G0-G1 transition phase. |
| Function | Required to maintain microtubule bundles in inner ear supporting cells, affording them with mechanical stiffness to transmit sound energy through the cochlea. |
| Protein Name | Growth Arrest-Specific Protein 2Gas-2 |
| Database Links | Reactome: R-HSA-264870 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberMembranePeripheral Membrane ProteinComponent Of The Microfilament SystemColocalizes With Actin Fibers At The Cell Border And Along The Stress Fibers In Growth-Arrested FibroblastsMainly Membrane-AssociatedWhen HyperphosphorylatedAccumulates At Membrane RufflesColocalizes With Detyrosinated Alpha-Tubulin Along The Length Of Microtubule Bundles In Inner And Outer Pillar Cells |
| Alternative Protein Names | Growth Arrest-Specific Protein 2 proteinGas-2 proteinGAS2 protein |
Information sourced from Uniprot.org