Human GAP43 (Neuromodulin) CLIA Kit for Quantitative Detection

Name: Human GAP43 (Neuromodulin) CLIA Kit for Quantitative Detection
SKU: STJC0000838
Availability: InStock

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SPECIFICATIONS

STJC0000838

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Short Description	This human GAP43 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications	CLIA
Reactivity	Human
Sensitivity	18.75pg/mL
Detection Limit	31.25~2000pg/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Chemiluminescence

Gene Symbol	GAP43
Gene ID	2596
Uniprot ID	NEUM_HUMAN
Specificity	This kit recognizes Human GAP43 in samples. No significant cross-reactivity or interference between Human GAP43 and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Post Translational Modifications	Phosphorylated. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity. Palmitoylated by ZDHHC3. Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2.
Function	This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Protein Name	Neuromodulin Axonal Membrane Protein Gap-43 Growth-Associated Protein 43 Neural Phosphoprotein B-50 Pp46
Database Links	Reactome: R-HSA-373760
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Projection Growth Cone Membrane Synapse Filopodium Membrane Perikaryon Dendrite Axon Cytoplasm Cytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes
Alternative CLIA Names	Neuromodulin CLIA kit Axonal Membrane Protein Gap-43 CLIA kit Growth-Associated Protein 43 CLIA kit Neural Phosphoprotein B-50 CLIA kit Pp46 CLIA kit GAP43 CLIA kit
Specificity	This kit recognizes Human GAP43 in samples. No significant cross-reactivity or interference between Human GAP43 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	94.41	287.04	773.36	102.98	274.69	735.86
Standard deviation	7.59	25.03	49.96	10.74	32.47	61.52
CV (%)	8.04	8.72	6.46	10.43	11.82	8.36