Human GAP43 (GAP43) Antibody Pair (STJAP00778)
General Information
| Short Description | This GAP43 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R39-2C-4/R81-6N-1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GAP43 |
| Gene ID | 2596 |
| Uniprot ID | NEUM_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity. Palmitoylated by ZDHHC3. Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2. |
| Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| Protein Name | NeuromodulinAxonal Membrane Protein Gap-43Growth-Associated Protein 43Neural Phosphoprotein B-50Pp46 |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionGrowth Cone MembraneSynapseFilopodium MembranePerikaryonDendriteAxonCytoplasmCytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes |
| Alternative Antibody Pair Names | Neuromodulin antibody pairAxonal Membrane Protein Gap-43 antibody pairGrowth-Associated Protein 43 antibody pairNeural Phosphoprotein B-50 antibody pairPp46 antibody pairGAP43 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human GAP43 (GAP43) Antibody Pair (STJAP00778)
This antibody pair is designed to detect human GAP43 (Growth Associated Protein 43, UniProt P17677). Reactivity has been confirmed for human samples only.
This antibody pair is validated for use in ELISA. It is intended for sandwich ELISA development where one antibody serves as the capture reagent and the other as the detection antibody.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2. Both have been affinity purified and are supplied as separate components.
The two antibodies are identified by clone IDs R39-2C-4 and R81-6N-1, both raised in rabbit. Both are monoclonal antibodies generated against a recombinant protein immunogen.
Working concentrations for both the capture and detection antibodies are to be determined by the end user. Titration experiments are recommended to establish optimal concentrations for the specific assay conditions being used.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquots should be kept at -20°C, and repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.