Human GAN (Gigaxonin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015455)

Name: Human GAN (Gigaxonin) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015455)
SKU: STJE0015455
Availability: InStock

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SPECIFICATIONS

STJE0015455

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Short Description	This GAN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Applications	ELISA
Reactivity	Human
Sensitivity	0.055ng/mL
Detection Limit	0.156-10ng/mL
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Storage Instruction	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time	3 hrs

Gene Symbol	GAN
Gene ID	8139
Uniprot ID	GAN_HUMAN
Immunogen Region	Ready-To-Use
Sample Type	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in brain, heart and muscle.
Post Translational Modifications	Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation.
Function	Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Protein Name	Gigaxonin Kelch-Like Protein 16
Database Links	Reactome: R-HSA-8951664 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Cytoskeleton
Alternative ELISA Names	Gigaxonin ELISA kit Kelch-Like Protein 16 ELISA kit GAN ELISA kit GAN1 ELISA kit KLHL16 ELISA kit
output

Information sourced from Uniprot.org