Human gamma Synuclein/SNCG (gamma Synuclein/SNCG) Antibody Pair (STJAP00777)
General Information
| Short Description | This gamma Synuclein/SNCG antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R19-5I-7/R97-7T-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SNCG |
| Gene ID | 6623 |
| Uniprot ID | SYUG_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. |
| Post Translational Modifications | Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. |
| Protein Name | Gamma-SynucleinBreast Cancer-Specific Gene 1 ProteinPersynSynoretinSr |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleAssociated With Centrosomes In Several Interphase CellsIn Mitotic CellsLocalized To The Poles Of The Spindle |
| Alternative Antibody Pair Names | Gamma-Synuclein antibody pairBreast Cancer-Specific Gene 1 Protein antibody pairPersyn antibody pairSynoretin antibody pairSr antibody pairSNCG antibody pairBCSG1 antibody pairPERSYN antibody pairPRSN antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human gamma Synuclein/SNCG (gamma Synuclein/SNCG) Antibody Pair (STJAP00777)
This antibody pair detects human gamma Synuclein (SNCG), corresponding to UniProt entry O76070. Reactivity has been confirmed for human samples only.
This antibody pair is validated for use in ELISA. No other assay formats are listed for this product.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2, and purified by affinity chromatography. The clone IDs are R19-5I-7 and R97-7T-9 respectively.
Optimal working dilutions for both antibodies are to be determined by the end user. Titration experiments are recommended to establish the appropriate concentrations for each specific experimental setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, and avoid repeated freeze/thaw cycles to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.