Human Gamma-glutamylcyclotransferase/GGCT protein (Recombinant) (His-Tag) (STJP017025)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Gamma-glutamylcyclotransferase/GGCT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GGCT |
| Gene ID | 79017 |
| Uniprot ID | GGCT_HUMAN |
| Accession Number | NP_076956 |
| Immunogen | Human |
| Immunogen Region | 1-188aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII KKGETQTL |
Additional Info
| Function | Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. |
| Protein Name | Gamma-GlutamylcyclotransferaseCytochrome C-Releasing Factor 21 |
| Database Links | Reactome: R-HSA-174403 |
| Cellular Localisation | |
| Alternative Protein Names | Gamma-Glutamylcyclotransferase proteinCytochrome C-Releasing Factor 21 proteinGGCT proteinC7orf24 proteinCRF21 protein |
Information sourced from Uniprot.org