Human Galectin-10/LGALS10 protein (Recombinant) (His-Tag) (STJP017170)

SKU:
STJP017170
£134.50 - £738.50
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Short Description :Recombinant-Human Galectin-10/LGALS10-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CLC
Gene ID:1178
Uniprot ID:LEG10_HUMAN
Accession Number:NP_001819.2
Immunogen:Human
Immunogen Region:1-142aa
Immunogen Sequence: MSLLPVPYTE AASLSTGSTV TIKGRPLACF LNEPYLQVDF HTEMKEESDI VFHFQVCFGR RVVMNSREYG AWKQQVESKN MPFQDGQEFE LSISVLPDKY QVMVNGQSSY TFDHRIKPEA VKMVQVWRDI SLTKFNVSYL KR
Tissue Specificity Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).
Function Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
Protein Name Galectin-10
Gal-10
Charcot-Leyden Crystal Protein
Clc
Eosinophil Lysophospholipase
Lysolecithin Acylhydrolase
Database Links
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Granule
Localized In Granules From Where It May Be Secreted Or Transported To Other Locations In The Cell
Alternative Protein Names Galectin-10 protein
Gal-10 protein
Charcot-Leyden Crystal Protein protein
Clc protein
Eosinophil Lysophospholipase protein
Lysolecithin Acylhydrolase protein
CLC protein
LGALS10 protein
LGALS10A protein

Information sourced from Uniprot.org