Human GAL3 (Galectin-3) Antibody Pair (STJAP00154)
General Information
| Short Description | This GAL3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | LGALS3 |
| Gene ID | 3958 |
| Uniprot ID | LEG3_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human GAL3 protein.Detection Immunogen: Recombinant Human GAL3 protein. |
Additional Info
| Function | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. |
| Protein Name | Galectin-3Gal-335 Kda LectinCarbohydrate-Binding Protein 35Cbp 35Galactose-Specific Lectin 3Galactoside-Binding ProteinGalbpIge-Binding ProteinL-31Laminin-Binding ProteinLectin L-29Mac-2 Antigen |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-879415Reactome: R-HSA-8939246Reactome: R-HSA-8941333 |
| Cellular Localisation | CytoplasmNucleusSecretedSecreted By A Non-Classical Secretory Pathway And Associates With The Cell SurfaceCan Be SecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Pair Names | Galectin-3 antibody pairGal-3 antibody pair35 Kda Lectin antibody pairCarbohydrate-Binding Protein 35 antibody pairCbp 35 antibody pairGalactose-Specific Lectin 3 antibody pairGalactoside-Binding Protein antibody pairGalbp antibody pairIge-Binding Protein antibody pairL-31 antibody pairLaminin-Binding Protein antibody pairLectin L-29 antibody pairMac-2 Antigen antibody pairLGALS3 antibody pairMAC2 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human GAL3 (Galectin-3) Antibody Pair (STJAP00154)
This antibody pair detects human Galectin-3 (GAL3), corresponding to UniProt entry P17931. Reactivity is confirmed for human samples only.
The capture antibody is an unconjugated mouse monoclonal antibody purified by Protein A, and the detection antibody is a biotin-conjugated goat polyclonal antibody purified by antigen affinity. Both components are supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair is validated for use in ELISA. No other assay formats are specified for this product.
Both the capture and detection antibodies were raised against recombinant human GAL3 protein. No additional immunogen region details are provided in the product specifications.
Both components should be stored at -20 degrees Celsius for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.