Human Gal-1/LGALS1 protein (Recombinant) (C-His) (STJP007292)

Name: Human Gal-1/LGALS1 protein (Recombinant) (C-His) (STJP007292)
SKU: STJP007292
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP007292

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Short Description	Recombinant-Human Gal-1/LGALS1-C-His protein was developed from e.coli for the region C-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
Protein Name	Galectin-1 Gal-1 14 Kda Laminin-Binding Protein Hlbp14 14 Kda Lectin Beta-Galactoside-Binding Lectin L-14-I Galaptin Hbl Hpl Lactose-Binding Lectin 1 Lectin Galactoside-Binding Soluble 1 Putative Mapk-Activating Protein Pm12 S-Lac Lectin 1
Database Links	Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Cytoplasm Can Be Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names	Galectin-1 protein Gal-1 protein 14 Kda Laminin-Binding Protein protein Hlbp14 protein 14 Kda Lectin protein Beta-Galactoside-Binding Lectin L-14-I protein Galaptin protein Hbl protein Hpl protein Lactose-Binding Lectin 1 protein Lectin Galactoside-Binding Soluble 1 protein Putative Mapk-Activating Protein Pm12 protein S-Lac Lectin 1 protein LGALS1 protein

Information sourced from Uniprot.org