Human G-CSF/CSF3 protein (Recombinant) (C-6His) (STJP001902)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human G-CSF/CSF3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro204) of human G-CSF/CSF3 (Accession #NP_757373.1) fused with and a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human G-CSF/CSF3-C-6His protein was developed in hek293 cells using the region Met1-Pro204. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | 1.Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 41-164 pg/mL. |
| Determination Method | ＜0.001 EU/Mu g |
Target Information
| Gene Symbol | CSF3 |
| Gene ID | 1440 |
| Uniprot ID | CSF3_HUMAN |
| Immunogen | Recombinant Human G-CSF/CSF3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro204) of human G-CSF/CSF3 (Accession #NP_757373.1) fused with and a 6×His tag at the C-terminus. |
| Immunogen Region | Met1-Pro204 |
| Immunogen Sequence | MAGPATQSPMKLMALQLLLW HSALWTVQEATPLGPASSLP QSFLLKCLEQVRKIQGDGAA LQEKLCATYKLCHPEELVLL GHSLGIPWAPLSSCPSQALQ LAGCLSQLHSGLFLYQGLLQ ALEGISPELGPTLDTLQLDV ADFATTIWQQMEELGMAPAL QPTQGAMPAFASAFQRRAGG VLVASHLQSFLEVSYRVLRH LAQP |
Additional Info
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| Protein Name | Granulocyte Colony-Stimulating FactorG-CsfPluripoietinFilgrastimLenograstim |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-6783783Reactome: R-HSA-9674555Reactome: R-HSA-9705462 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Granulocyte Colony-Stimulating Factor proteinG-Csf proteinPluripoietin proteinFilgrastim proteinLenograstim proteinCSF3 proteinC17orf33 proteinGCSF protein |
Information sourced from Uniprot.org