Human FXYD5/Dysadherin protein (Recombinant) (His-Tag) (STJP018075)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FXYD5/Dysadherin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FXYD5 |
| Gene ID | 53827 |
| Uniprot ID | FXYD5_HUMAN |
| Accession Number | NP_001158077.1 |
| Immunogen | Human |
| Immunogen Region | 22-145aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 5Dysadherin |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinBasolateral Cell MembraneIn Kidneys Localizes To The Basolateral Membrane Of The Connecting Tubule |
| Alternative Protein Names | Fxyd Domain-Containing Ion Transport Regulator 5 proteinDysadherin proteinFXYD5 proteinDYSAD proteinIWU1 proteinHSPC113 proteinUNQ2561 proteinPRO6241 protein |
Information sourced from Uniprot.org