Human FUT2 protein (Recombinant) (N-His) (STJP006656)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FUT2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FUT2 |
| Gene ID | 2524 |
| Uniprot ID | FUT2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln29-His343 |
Additional Info
| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 2Alpha(1 -2ft 2Fucosyltransferase 2Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2Se2Secretor Blood Group Alpha-2-FucosyltransferaseSecretor FactorSeType 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 |
| Database Links | Reactome: R-HSA-9033807Reactome: R-HSA-9037629Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Protein Names | Galactoside Alpha-(1 -2-Fucosyltransferase 2 proteinAlpha(1 -2ft 2 proteinFucosyltransferase 2 proteinGdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2 proteinSe2 proteinSecretor Blood Group Alpha-2-Fucosyltransferase proteinSecretor Factor proteinSe proteinType 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 proteinType 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 proteinFUT2 proteinSEC2 protein |
Information sourced from Uniprot.org