Human FTH1 protein (Recombinant) (Tag free) (STJP014354)

SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP014354-100
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General Information

Short DescriptionRecombinant-Human FTH1-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications.
ApplicationsELISA/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt.
Endotoxin< 1 EU/ยตg as determined by LAL test.

Target Information

Gene SymbolFTH1
Gene ID2495
Uniprot IDFRIH_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Ser183

Additional Info

Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron.
Protein Name Ferritin Heavy Chain
Ferritin H Subunit
Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed
Database Links Reactome: R-HSA-3000480
Reactome: R-HSA-432722
Reactome: R-HSA-6798695
Reactome: R-HSA-917937
Cellular Localisation Cytoplasm
Lysosome
Cytoplasmic Vesicle
Autophagosome
Alternative Protein Names Ferritin Heavy Chain protein
Ferritin H Subunit protein
Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed protein
FTH1 protein
FTH protein
FTHL6 protein
OK protein
SW-cl.84 protein
PIG15 protein

Information sourced from Uniprot.org

Citations

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