Human FRS3 protein (Recombinant) (N-His) (STJP016348)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FRS3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | FRS3 |
| Gene ID | 10817 |
| Uniprot ID | FRS3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn111 |
Additional Info
| Function | Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. |
| Protein Name | Fibroblast Growth Factor Receptor Substrate 3Fgfr Substrate 3Fgfr-Signaling Adaptor Snt2Suc1-Associated Neurotrophic Factor Target 2Snt-2 |
| Database Links | Reactome: R-HSA-5654693Reactome: R-HSA-5654700Reactome: R-HSA-5654706Reactome: R-HSA-5654712Reactome: R-HSA-5673001Reactome: R-HSA-9028731Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-9725370 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Protein Names | Fibroblast Growth Factor Receptor Substrate 3 proteinFgfr Substrate 3 proteinFgfr-Signaling Adaptor Snt2 proteinSuc1-Associated Neurotrophic Factor Target 2 proteinSnt-2 proteinFRS3 protein |
Information sourced from Uniprot.org