Human FPR1 (Formyl Peptide Receptor 1) Sandwich ELISA Kit (STJE0008977)
SPECIFICATIONS
General Information
| Short Description | This FPR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.062ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | FPR1 |
| Gene ID | 2357 |
| Uniprot ID | FPR1_HUMAN |
| Sample Type | cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | Neutrophils. |
| Post Translational Modifications | Phosphorylated.which is necessary for desensitization. |
| Function | High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis. |
| Protein Name | Fmet-Leu-Phe ReceptorFmlp ReceptorN-Formyl Peptide ReceptorFprN-Formylpeptide Chemoattractant Receptor |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-444473Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInternalizes In Presence Of Its LigandsFmlpTafa4 And Ctsg |
| Alternative ELISA Names | Fmet-Leu-Phe Receptor ELISA kitFmlp Receptor ELISA kitN-Formyl Peptide Receptor ELISA kitFpr ELISA kitN-Formylpeptide Chemoattractant Receptor ELISA kitFPR1 ELISA kit |
| output |
Information sourced from Uniprot.org