Human Follistatin-like 1/FSTL1 protein (Recombinant) (No-Tag) (STJP003068)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human Follistatin-like protein 1/FSTL1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ile308) of Human Follistatin-like protein 1/FSTL1 (Accession #NP_009016.1) fused with a His
General Information
| Short Description | Recombinant-Human Follistatin-like 1/FSTL1-No-Tag protein was developed in e.coli using the region Glu21-Ile308. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.01 EU/Mu g |
Target Information
| Gene Symbol | FSTL1 |
| Gene ID | 11167 |
| Uniprot ID | FSTL1_HUMAN |
| Immunogen | Recombinant Human Follistatin-like protein 1/FSTL1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ile308) of Human Follistatin-like protein 1/FSTL1 (Accession #NP_009016.1) fused with a His |
| Immunogen Region | Glu21-Ile308 |
| Immunogen Sequence | MSDSEVNQEAKPEVKPEVKP ETHINLKVSDGSSEIFFKIK KTTPLRRLMEAFAKRQGKEM DSLRFLYDGIRIQADQTPED LDMEDNDIIEAHREQIGG |
Additional Info
| Tissue Specificity | Overexpressed in synovial tissues from rheumatoid arthritis. |
| Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. |
| Protein Name | Follistatin-Related Protein 1Follistatin-Like Protein 1 |
| Database Links | Reactome: R-HSA-201451Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Follistatin-Related Protein 1 proteinFollistatin-Like Protein 1 proteinFSTL1 proteinFRP protein |
Information sourced from Uniprot.org