Human FOLH1/PSMA protein (Recombinant) (N-Strep) (STJP006650)
SPECIFICATIONS
HostInsect Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FOLH1/PSMA-N-Strep protein was developed from insect cells for the region N-Strep. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Insect Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FOLH1 |
| Gene ID | 2346 |
| Uniprot ID | FOLH1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys44-Ala750 |
Additional Info
| Post Translational Modifications | The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked. |
| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
| Protein Name | Glutamate Carboxypeptidase 2Cell Growth-Inhibiting Gene 27 ProteinFolate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane AntigenPsmPsmaPteroylpoly-Gamma-Glutamate Carboxypeptidase |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform Psma': Cytoplasm |
| Alternative Protein Names | Glutamate Carboxypeptidase 2 proteinCell Growth-Inhibiting Gene 27 Protein proteinFolate Hydrolase 1 proteinFolylpoly-Gamma-Glutamate Carboxypeptidase proteinFgcp proteinGlutamate Carboxypeptidase Ii proteinGcpii proteinMembrane Glutamate Carboxypeptidase proteinMgcp proteinN-Acetylated-Alpha-Linked Acidic Dipeptidase I proteinNaaladase I proteinProstate-Specific Membrane Antigen proteinPsm proteinPsma proteinPteroylpoly-Gamma-Glutamate Carboxypeptidase proteinFOLH1 proteinFOLH proteinNAALAD1 proteinPSM proteinPSMA proteinGIG27 protein |
Information sourced from Uniprot.org