Human FNTA protein (Recombinant) (N-His) (STJP004811)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FNTA-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FNTA |
| Gene ID | 2339 |
| Uniprot ID | FNTA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met51-Lys366 |
Additional Info
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
| Protein Name | Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit AlphaCaax Farnesyltransferase Subunit AlphaFtase-AlphaRas Proteins Prenyltransferase Subunit AlphaType I Protein Geranyl-Geranyltransferase Subunit AlphaGgtase-I-Alpha |
| Database Links | Reactome: R-HSA-111465Reactome: R-HSA-2514859Reactome: R-HSA-9648002Reactome: R-HSA-9679191 |
| Cellular Localisation | |
| Alternative Protein Names | Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha proteinCaax Farnesyltransferase Subunit Alpha proteinFtase-Alpha proteinRas Proteins Prenyltransferase Subunit Alpha proteinType I Protein Geranyl-Geranyltransferase Subunit Alpha proteinGgtase-I-Alpha proteinFNTA protein |
Information sourced from Uniprot.org