Human FNDC5 (Fibronectin Type Iii Domain-Containing Protein 5) Sandwich ELISA Kit (STJE0000767)
SPECIFICATIONS
ConjugationBiotin
General Information
| Short Description | This Fibronectin Type Iii Domain-Containing Protein 5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and cell culture supernates. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 6.9 pg/mL |
| Detection Limit | 312-2000 pg/ml |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Storage Instruction | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time | 4 hours |
| Detection | Colorimetric |
Target Information
| Gene Symbol | FNDC5 |
| Gene ID | 252995 |
| Uniprot ID | FNDC5_HUMAN |
| Sample Type | serum, plasma and cell culture supernates |
Additional Info
| Tissue Specificity | Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. |
| Post Translational Modifications | The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated. |
| Function | Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. |
| Protein Name | Fibronectin Type Iii Domain-Containing Protein 5Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin |
| Database Links | |
| Cellular Localisation | Fibronectin Type Iii Domain-Containing Protein 5: Cell MembraneSingle-Pass Membrane ProteinPeroxisome MembraneImported Into Peroxisomes Through The Pex5 Receptor PathwayIrisin: SecretedDetected In Plasma Following Endurance Exercise |
| Alternative ELISA Names | Fibronectin Type Iii Domain-Containing Protein 5 ELISA kitFibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin ELISA kitFNDC5 ELISA kitFRCP2 ELISA kit |
| output |
Information sourced from Uniprot.org