Human FMO2 protein (Recombinant) (N-His) (STJP006348)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FMO2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FMO2 |
| Gene ID | 2327 |
| Uniprot ID | FMO2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly295-Asn469 |
Additional Info
| Function | Catalyzes the oxidative metabolism of numerous xenobiotics, including mainly therapeutic drugs and insecticides that contain a soft nucleophile, most commonly nitrogen and sulfur and participates to their bioactivation. Specifically catalyzes S-oxygenation of sulfur derived compounds such as thioureas-derived compounds, thioetherorganophosphates to their sulfenic acid. In vitro, catalyzes S-oxygenation of the second-line antitubercular drugs thiacetazone (TAZ) and ethionamide (ETA), forming a sulfinic acid and a carbodiimide via a postulated sulfenic acid intermediate. Also catalyzes S-oxygenation of the thioether-containing organophosphate insecticides, phorate and disulfoton. |
| Protein Name | Flavin-Containing Monooxygenase 2Dimethylaniline Oxidase 2Fmo 1b1Pulmonary Flavin-Containing Monooxygenase 2Fmo 2 |
| Database Links | Reactome: R-HSA-217271 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Protein Names | Flavin-Containing Monooxygenase 2 proteinDimethylaniline Oxidase 2 proteinFmo 1b1 proteinPulmonary Flavin-Containing Monooxygenase 2 proteinFmo 2 proteinFMO2 protein |
Information sourced from Uniprot.org