Human FLII (Flightless I Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015319)
SPECIFICATIONS
General Information
| Short Description | This FLII Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 29.2pg/mL |
| Detection Limit | 78.1-5000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | FLII |
| Gene ID | 2314 |
| Uniprot ID | FLII_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Strongest expression in skeletal muscle with high expression also in the heart and lung. |
| Post Translational Modifications | |
| Function | Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. |
| Protein Name | Protein Flightless-1 Homolog |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionPodosomeCell JunctionFocal AdhesionColocalizes To Actin-Rich Structures In Blastocysts AndTogether With HrasRhoa And Cdc42In Migrating FibroblastsLocalizes To CentrosomesLocalized To The Core Of Macrophage Podosomes |
| Alternative ELISA Names | Protein Flightless-1 Homolog ELISA kitFLII ELISA kitFLIL ELISA kit |
| output |
Information sourced from Uniprot.org