Human FKBP22/FKBP14 protein (Recombinant) (His-Tag) (STJP016744)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FKBP22/FKBP14-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 240nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 37C in Tris-Hcl pH8.0 using chymotrypsin. |
Target Information
| Gene Symbol | FKBP14 |
| Gene ID | 55033 |
| Uniprot ID | FKB14_HUMAN |
| Accession Number | NP_060416 |
| Immunogen | Human |
| Immunogen Region | 20-211aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL |
Additional Info
| Function | PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp14Ppiase Fkbp1422 Kda Fk506-Binding Protein22 Kda FkbpFkbp-22Fk506-Binding Protein 14Fkbp-14Rotamase |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp14 proteinPpiase Fkbp14 protein22 Kda Fk506-Binding Protein protein22 Kda Fkbp proteinFkbp-22 proteinFk506-Binding Protein 14 proteinFkbp-14 proteinRotamase proteinFKBP14 proteinFKBP22 proteinUNQ322 proteinPRO381 protein |
Information sourced from Uniprot.org