Human FHL2 protein (Recombinant) (His-Tag) (STJP018950)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FHL2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FHL2 |
| Gene ID | 2274 |
| Uniprot ID | FHL2_HUMAN |
| Accession Number | NP_001034581 |
| Immunogen | Human |
| Immunogen Region | 1-279aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in skeletal muscle and heart. |
| Function | May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes. |
| Protein Name | Four And A Half Lim Domains Protein 2Fhl-2Lim Domain Protein DralSkeletal Muscle Lim-Protein 3Slim-3 |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | CytoplasmNucleusMyofibrilSarcomereZ Line |
| Alternative Protein Names | Four And A Half Lim Domains Protein 2 proteinFhl-2 proteinLim Domain Protein Dral proteinSkeletal Muscle Lim-Protein 3 proteinSlim-3 proteinFHL2 proteinDRAL proteinSLIM3 protein |
Information sourced from Uniprot.org