Human FGFR-5/FGFRL1 protein (Recombinant) (C-His) (STJP000909)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human FGFR-5/FGFRL1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala 25-Pro 378 ) of human FGF R5/FGFRL1 (Accession #NP_068742.2) fused with a 6ΓHis tag at the C-terminus.
General Information
| Short Description | Recombinant-Human FGFR-5/FGFRL1-C-His protein was developed in hek293 cells using the region Ala 25-Pro 378. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | FGFRL1 |
| Gene ID | 53834 |
| Uniprot ID | FGRL1_HUMAN |
| Immunogen | Recombinant Human FGFR-5/FGFRL1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala 25-Pro 378 ) of human FGF R5/FGFRL1 (Accession #NP_068742.2) fused with a 6ΓHis tag at the C-terminus. |
| Immunogen Region | Ala 25-Pro 378 |
| Immunogen Sequence | ARGPPKMADKVVPRQVARLG RTVRLQCPVEGDPPPLTMWT KDGRTIHSGWSRFRVLPQGL KVKQVEREDAGVYVCKATNG FGSLSVNYTLVVLDDISPGK ESLGPDSSSGGQEDPASQQW ARPRFTQPSKMRRRVIARPV GSSVRLKCVASGHPRPDITW MKDDQALTRPEAAEPRKKKW TLSLKNLRPEDSGKYTCRVS NRAGAINATYKVDVIQRTRS KPVLTGTHPVNTTVDFGGT |
Additional Info
| Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. |
| Function | Has a negative effect on cell proliferation. |
| Protein Name | Fibroblast Growth Factor Receptor-Like 1Fgf Receptor-Like Protein 1Fgf Homologous Factor ReceptorFgfr-Like ProteinFibroblast Growth Factor Receptor 5Fgfr-5 |
| Database Links | Reactome: R-HSA-5658623 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinPredominantly Localized In The Plasma Membrane But Also Detected In The Golgi And In Secretory Vesicles |
| Alternative Protein Names | Fibroblast Growth Factor Receptor-Like 1 proteinFgf Receptor-Like Protein 1 proteinFgf Homologous Factor Receptor proteinFgfr-Like Protein proteinFibroblast Growth Factor Receptor 5 proteinFgfr-5 proteinFGFRL1 proteinFGFR5 proteinFHFR proteinUNQ480 proteinPRO943 protein |
Information sourced from Uniprot.org