Human FGFBP3 protein (Recombinant) (STJP001856)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encodingHuman Fibroblast growth factor binding protein-FGFBP3 (ARG28-GLY258) extracellular domain including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human FGFBP3-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | FGFBP3 |
| Gene ID | 143282 |
| Uniprot ID | FGFP3_HUMAN |
| Immunogen | Optimized DNA sequence encodingHuman Fibroblast growth factor binding protein-FGFBP3 (ARG28-GLY258) extracellular domain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | ARG28-GLY258 |
Additional Info
| Function | Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability. |
| Protein Name | Fibroblast Growth Factor-Binding Protein 3Fgf-Bp3Fgf-Binding Protein 3Fgfbp-3 |
| Database Links | Reactome: R-HSA-190377 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Fibroblast Growth Factor-Binding Protein 3 proteinFgf-Bp3 proteinFgf-Binding Protein 3 proteinFgfbp-3 proteinFGFBP3 proteinC10orf13 proteinPSEC0101 protein |
Information sourced from Uniprot.org