| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human FGFBP1-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: |
FGFBP1 |
| Gene ID: |
9982 |
| Uniprot ID: |
FGFP1_HUMAN |
| Immunogen Region: |
LYS24-CYS234 |
| Immunogen: |
Optimized DNA sequence encodingHuman Fibroblast growth factor binding protein-FGFBP1 (LYS24-CYS234) extracellular domain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. |
| Function | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. |
| Protein Name | Fibroblast Growth Factor-Binding Protein 1Fgf-BpFgf-Bp1Fgf-Binding Protein 1Fgfbp-117 Kda Heparin-Binding Growth Factor-Binding Protein17 Kda Hbgf-Binding ProteinHbp17 |
| Database Links | Reactome: R-HSA-190377 |
| Cellular Localisation | SecretedExtracellular SpaceCell MembranePeripheral Membrane ProteinExtracellular And Plasma Membrane-AssociatedColocalizes With Hspg2 In The Pericellular Environment Of Squamous Cell Carcinomas |
| Alternative Protein Names | Fibroblast Growth Factor-Binding Protein 1 proteinFgf-Bp proteinFgf-Bp1 proteinFgf-Binding Protein 1 proteinFgfbp-1 protein17 Kda Heparin-Binding Growth Factor-Binding Protein protein17 Kda Hbgf-Binding Protein proteinHbp17 proteinFGFBP1 proteinFGFBP proteinHBP17 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
