Human FGF-8b protein (Recombinant) (His-Tag) (STJP019520)

SPECIFICATIONS
HostHEK293 Cells
ImmunogenHuman
STJP019520
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General Information

Short DescriptionRecombinant-Human FGF-8b-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Bioactivity
HostHEK293 Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol.
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin< 1 EU per 1ug of protein (determined by LAL method)
ImmunoreactivityMeasured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells in the presence of 10 ug/ml of heparin. The ED50 range ≤ 5 ug/ml.

Target Information

Gene SymbolFGF8
Gene ID2253
Uniprot IDFGF8_HUMAN
Accession NumberNP_006110.1
ImmunogenHuman
Immunogen Region23-215aa
Immunogen SequenceQVTVQ SSPNFTQHVR EQSLVTDQLS RRLIRTYQLY SRTSGKHVQV LANKRINAMA EDGDPFAKLI VETDTFGSRV RVRGAETGLY ICMNKKGKLI AKSNGKGKDC VFTEIVLENN YTALQNAKYE GWYMAFTRKG RPRKGSKTRQ HQREVHFMKR LPRGHHTTEQ SLRFEFLNYP PFTRSLRGSQ RTWAPEPR

Additional Info

Function Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
Protein Name Fibroblast Growth Factor 8
Fgf-8
Androgen-Induced Growth Factor
Aigf
Heparin-Binding Growth Factor 8
Hbgf-8
Database Links Reactome: R-HSA-109704 P55075-1
Reactome: R-HSA-1257604 P55075-1
Reactome: R-HSA-1839122 P55075-1
Reactome: R-HSA-1839130 P55075-1
Reactome: R-HSA-190322 P55075-1
Reactome: R-HSA-190371 P55075-1
Reactome: R-HSA-190372 P55075-1
Reactome: R-HSA-190373 P55075-1
Reactome: R-HSA-190375 P55075-1
Reactome: R-HSA-2033519 P55075-1
Reactome: R-HSA-2219530 P55075-1
Reactome: R-HSA-5654219 P55075-1
Reactome: R-HSA-5654221 P55075-1
Reactome: R-HSA-5654227 P55075-1
Reactome: R-HSA-5654228 P55075-1
Reactome: R-HSA-5654687 P55075-1
Reactome: R-HSA-5654688 P55075-1
Reactome: R-HSA-5654689 P55075-1
Reactome: R-HSA-5654693 P55075-1
Reactome: R-HSA-5654695 P55075-1
Reactome: R-HSA-5654699 P55075-1
Reactome: R-HSA-5654700 P55075-1
Reactome: R-HSA-5654704 P55075-1
Reactome: R-HSA-5654706 P55075-1
Reactome: R-HSA-5654710 P55075-1
Reactome: R-HSA-5654712 P55075-1
Reactome: R-HSA-5654719 P55075-1
Reactome: R-HSA-5654720 P55075-1
Reactome: R-HSA-5654726 P55075-1
Reactome: R-HSA-5654727 P55075-1
Reactome: R-HSA-5654732 P55075-1
Reactome: R-HSA-5654733 P55075-1
Reactome: R-HSA-5655253 P55075-1
Reactome: R-HSA-5655302 P55075-1
Reactome: R-HSA-5655332 P55075-1
Reactome: R-HSA-5658623 P55075-1
Reactome: R-HSA-5673001 P55075-1
Reactome: R-HSA-6811558 P55075-1
Reactome: R-HSA-9832991
Cellular Localisation Secreted
Alternative Protein Names Fibroblast Growth Factor 8 protein
Fgf-8 protein
Androgen-Induced Growth Factor protein
Aigf protein
Heparin-Binding Growth Factor 8 protein
Hbgf-8 protein
FGF8 protein
AIGF protein

Information sourced from Uniprot.org

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