Human FGF-21 (L174P) protein (Recombinant) (His-Tag) (STJP019386)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FGF-21 (L174P)-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | FGF21 |
| Gene ID | 26291 |
| Uniprot ID | FGF21_HUMAN |
| Accession Number | NP_061986 |
| Immunogen | Human |
| Immunogen Region | 29-209aa |
| Immunogen Sequence |
Additional Info
| Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
| Protein Name | Fibroblast Growth Factor 21Fgf-21 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Fibroblast Growth Factor 21 proteinFgf-21 proteinFGF21 proteinUNQ3115 proteinPRO10196 protein |
Information sourced from Uniprot.org