Human FGD4/FRABP protein (Recombinant) (N-His) (STJP008499)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FGD4/FRABP-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FGD4 |
| Gene ID | 121512 |
| Uniprot ID | FGD4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser545-Glu742 |
Additional Info
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4Actin Filament-Binding Protein FrabinFgd1-Related F-Actin-Binding ProteinZinc Finger Fyve Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionFilopodiumConcentrated In Filopodia And Poorly Detected At LamellipodiaBinds Along The Sides Of Actin Fibers |
| Alternative Protein Names | Fyve - Rhogef And Ph Domain-Containing Protein 4 proteinActin Filament-Binding Protein Frabin proteinFgd1-Related F-Actin-Binding Protein proteinZinc Finger Fyve Domain-Containing Protein 6 proteinFGD4 proteinFRABP proteinZFYVE6 protein |
Information sourced from Uniprot.org