Human Ferritin heavy chain 1/FTH1 protein (Recombinant) (No-Tag) (STJP019627)

Name: Human Ferritin heavy chain 1/FTH1 protein (Recombinant) (No-Tag) (STJP019627)
SKU: STJP019627
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP019627

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Short Description	Recombinant-Human Ferritin heavy chain 1/FTH1-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 7.5) containing, 10% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	FTH1
Gene ID	2495
Uniprot ID	FRIH_HUMAN
Accession Number	NP_002023.2
Immunogen	Human
Immunogen Region	1-183aa
Immunogen Sequence	MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES

Tissue Specificity	Expressed in the liver.
Function	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron.
Protein Name	Ferritin Heavy Chain Ferritin H Subunit Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed
Database Links	Reactome: R-HSA-3000480 Reactome: R-HSA-432722 Reactome: R-HSA-6798695 Reactome: R-HSA-917937
Cellular Localisation	Cytoplasm Lysosome Cytoplasmic Vesicle Autophagosome
Alternative Protein Names	Ferritin Heavy Chain protein Ferritin H Subunit protein Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed protein FTH1 protein FTH protein FTHL6 protein OK protein SW-cl.84 protein PIG15 protein

Information sourced from Uniprot.org