Human Ferredoxin 1/FDX1 protein (Recombinant) (T7-Tag) (STJP016502)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Ferredoxin 1/FDX1-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | FDX1 |
| Gene ID | 2230 |
| Uniprot ID | ADX_HUMAN |
| Accession Number | NP_004100.1 |
| Immunogen | Human |
| Immunogen Region | 61-184aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level). |
| Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1Hepatoredoxin |
| Database Links | Reactome: R-HSA-1362409Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Adrenodoxin - Mitochondrial proteinAdrenal Ferredoxin proteinFerredoxin-1 proteinHepatoredoxin proteinFDX1 proteinADX protein |
Information sourced from Uniprot.org