Human FDX1 protein (Recombinant) (N-His) (STJP008334)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FDX1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FDX1 |
| Gene ID | 2230 |
| Uniprot ID | ADX_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp65-Ser184 |
Additional Info
| Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1Hepatoredoxin |
| Database Links | Reactome: R-HSA-1362409Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Adrenodoxin - Mitochondrial proteinAdrenal Ferredoxin proteinFerredoxin-1 proteinHepatoredoxin proteinFDX1 proteinADX protein |
Information sourced from Uniprot.org