Human FcRH5/FcRL5 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001583)
SPECIFICATIONS
HostHEK293
ConjugationBiotin
ImmunogenDNA sequence encoding Human FcRH5/FcRL5 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
General Information
| Short Description | Recombinant-Human FcRH5/FcRL5-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Dilution Range | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Target Information
| Gene Symbol | FCRL5 |
| Gene ID | 83416 |
| Uniprot ID | FCRL5_HUMAN |
| Immunogen | DNA sequence encoding Human FcRH5/FcRL5 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Immunogen Region | Gln16-Gly851 |
Additional Info
| Function | Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. |
| Protein Name | Fc Receptor-Like Protein 5Fcr-Like Protein 5Fcrl5Bxmas1Fc Receptor Homolog 5Fcrh5Immune Receptor Translocation-Associated Protein 2Cd Antigen Cd307e |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Fc Receptor-Like Protein 5 proteinFcr-Like Protein 5 proteinFcrl5 proteinBxmas1 proteinFc Receptor Homolog 5 proteinFcrh5 proteinImmune Receptor Translocation-Associated Protein 2 proteinCd Antigen Cd307e proteinFCRL5 proteinFCRH5 proteinIRTA2 proteinUNQ503 proteinPRO820 protein |
Information sourced from Uniprot.org