Human FCN1 protein (Recombinant) (N-His) (STJP003167)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FCN1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FCN1 |
| Gene ID | 2219 |
| Uniprot ID | FCN1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala30-Ala326 |
Additional Info
| Function | Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
| Protein Name | Ficolin-1Collagen/Fibrinogen Domain-Containing Protein 1Ficolin-AFicolin-AlphaM-Ficolin |
| Database Links | Reactome: R-HSA-166662Reactome: R-HSA-166663Reactome: R-HSA-2855086Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedCell MembranePeripheral Membrane ProteinExtracellular SideFound On The Monocyte And Granulocyte Surface |
| Alternative Protein Names | Ficolin-1 proteinCollagen/Fibrinogen Domain-Containing Protein 1 proteinFicolin-A proteinFicolin-Alpha proteinM-Ficolin proteinFCN1 proteinFCNM protein |
Information sourced from Uniprot.org