Human Fc Epsilon R 2/CD23 (Low Affinity Immunoglobulin Epsilon Fc Receptor) Antibody Pair (STJAP00386)
SPECIFICATIONS
HostGoat/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human Fc Epsilon R 2/CD23 protien.Detection Immunogen: Recombinant Human Fc Epsilon R 2/CD23 protien.
General Information
| Short Description | This Fc Epsilon R 2/CD23 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | FCER2 |
| Gene ID | 2208 |
| Uniprot ID | FCER2_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human Fc Epsilon R 2/CD23 protien.Detection Immunogen: Recombinant Human Fc Epsilon R 2/CD23 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc ReceptorBlast-2C-Type Lectin Domain Family 4 Member JFc-Epsilon-RiiImmunoglobulin E-Binding FactorLymphocyte Ige ReceptorCd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form |
| Database Links | Reactome: R-HSA-2197563Reactome: R-HSA-6783783Reactome: R-HSA-6785807 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorSecretedAlso Exists As A Soluble Excreted FormScd23 |
| Alternative Antibody Pair Names | Low Affinity Immunoglobulin Epsilon Fc Receptor antibody pairBlast-2 antibody pairC-Type Lectin Domain Family 4 Member J antibody pairFc-Epsilon-Rii antibody pairImmunoglobulin E-Binding Factor antibody pairLymphocyte Ige Receptor antibody pairCd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody pairFCER2 antibody pairCD23A antibody pairCLEC4J antibody pairFCE2 antibody pairIGEBF antibody pair |
Information sourced from Uniprot.org