Human FBP2 protein (Recombinant) (N-His) (STJP003173)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP003173
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General Information

Short DescriptionRecombinant-Human FBP2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolFBP2
Gene ID8789
Uniprot IDF16P2_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Leu212

Additional Info

Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Protein Name Fructose-1 -6-Bisphosphatase Isozyme 2
Fbpase 2
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2
Muscle Fbpase
Database Links Reactome: R-HSA-70263
Cellular Localisation Cell Junction
Cytoplasm
Nucleus
Myofibril
Sarcomere
Z Line
In Neonatal Cardiomyocytes
Distributed Throughout The Cytosol
Accumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent Cells
And Also Located In The Nucleus
Dissociates From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration
In Muscle Precursor Cells
Localizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative Phase
While Mainly Localizing To The Cytoplasm At The Differentiation Phase
Colocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal Muscle
Dissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration
Alternative Protein Names Fructose-1 -6-Bisphosphatase Isozyme 2 protein
Fbpase 2 protein
D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 protein
Muscle Fbpase protein
FBP2 protein

Information sourced from Uniprot.org

Citations

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