Human FBP2 protein (Recombinant) (His-Tag) (STJP019237)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human FBP2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 1, 500pmol/min/ug obtained by measuring the increase of NADPH in absorbance at 340 nm resulting from the reduction of NADP. One unit will oxidize 1.0pmole of fructose 1, 6 diphosphate to fructose 6-phosphate and inorganic phosp |
Target Information
| Gene Symbol | FBP2 |
| Gene ID | 8789 |
| Uniprot ID | F16P2_HUMAN |
| Accession Number | NP_003828 |
| Immunogen | Human |
| Immunogen Region | 1-339aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in skeletal muscle (at protein level). |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
| Protein Name | Fructose-1 -6-Bisphosphatase Isozyme 2Fbpase 2D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2Muscle Fbpase |
| Database Links | Reactome: R-HSA-70263 |
| Cellular Localisation | Cell JunctionCytoplasmNucleusMyofibrilSarcomereZ LineIn Neonatal CardiomyocytesDistributed Throughout The CytosolAccumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent CellsAnd Also Located In The NucleusDissociates From The Z Line Following An Increase In Cytosolic Ca(2+) ConcentrationIn Muscle Precursor CellsLocalizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative PhaseWhile Mainly Localizing To The Cytoplasm At The Differentiation PhaseColocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal MuscleDissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration |
| Alternative Protein Names | Fructose-1 -6-Bisphosphatase Isozyme 2 proteinFbpase 2 proteinD-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 proteinMuscle Fbpase proteinFBP2 protein |
Information sourced from Uniprot.org