Human FBLN5 protein (Recombinant) (N-His) (STJP006140)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP006140
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General Information

Short DescriptionRecombinant-Human FBLN5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolFBLN5
Gene ID10516
Uniprot IDFBLN5_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionLeu99-Cys205

Additional Info

Post Translational Modifications N-glycosylated.
Function Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.
Protein Name Fibulin-5
Fibl-5
Developmental Arteries And Neural Crest Egf-Like Protein
Dance
Urine P50 Protein
Up50
Database Links Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Co-Localizes With Eln In Elastic Fibers
Alternative Protein Names Fibulin-5 protein
Fibl-5 protein
Developmental Arteries And Neural Crest Egf-Like Protein protein
Dance protein
Urine P50 Protein protein
Up50 protein
FBLN5 protein
DANCE protein
UNQ184 protein
PRO210 protein

Information sourced from Uniprot.org

Citations

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