Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
Post Translational Modifications | N-glycosylated. |
Function | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
Protein Name | Pseudokinase Fam20a |
Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | SecretedGolgi ApparatusEndoplasmic Reticulum |
Alternative ELISA Names | Pseudokinase Fam20a ELISA kitFAM20A ELISA kitUNQ9388 ELISA kitPRO34279 ELISA kit |
output | |
Information sourced from Uniprot.org