Human FAHD1 protein (Recombinant) (N-His) (STJP016012)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FAHD1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | FAHD1 |
| Gene ID | 81889 |
| Uniprot ID | FAHD1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala25-Tyr221 |
Additional Info
| Function | Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate. It is thereby required to maximize aerobic respiration efficiency by preventing succinate dehydrogenase inhibition. Also acts as a weak oxaloacetate decarboxylase (ODx), catalyzing the decarboxylation of oxaloacetate (OAA) to pyruvate and CO(2), and as such is likely a regulatory enzyme in the TCA cycle. Also displays acylpyruvase activity, being able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Exhibits only a weak hydrolase activity on methylacetopyruvate and acetylacetone, and no activity toward acetoacetyl-CoA. |
| Protein Name | Oxaloacetate Tautomerase Fahd1 - MitochondrialAcylpyruvase Fahd1Fumarylacetoacetate Hydrolase Domain-Containing Protein 1Fah Domain-Containing Protein 1Oxaloacetate DecarboxylaseOaa DecarboxylaseOdxYisk-Like Protein |
| Database Links | Reactome: R-HSA-70268 |
| Cellular Localisation | MitochondrionCytoplasmCytosol |
| Alternative Protein Names | Oxaloacetate Tautomerase Fahd1 - Mitochondrial proteinAcylpyruvase Fahd1 proteinFumarylacetoacetate Hydrolase Domain-Containing Protein 1 proteinFah Domain-Containing Protein 1 proteinOxaloacetate Decarboxylase proteinOaa Decarboxylase proteinOdx proteinYisk-Like Protein proteinFAHD1 proteinC16orf36 proteinYISKL protein |
Information sourced from Uniprot.org