Human FAF2 protein (Recombinant) (N-His) (STJP010984)

Name: Human FAF2 protein (Recombinant) (N-His) (STJP010984)
SKU: STJP010984
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP010984

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Short Description	Recombinant-Human FAF2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis. Involved in stress granule disassembly: associates with ubiquitinated G3BP1 in response to heat shock, thereby promoting interaction between ubiquitinated G3BP1 and VCP, followed by G3BP1 extraction from stress granules and stress granule disassembly.
Protein Name	Fas-Associated Factor 2 Ubx Domain-Containing Protein 3b Ubx Domain-Containing Protein 8
Database Links	Reactome: R-HSA-6798695 Reactome: R-HSA-8980692
Cellular Localisation	Cytoplasm Lipid Droplet Endoplasmic Reticulum
Alternative Protein Names	Fas-Associated Factor 2 protein Ubx Domain-Containing Protein 3b protein Ubx Domain-Containing Protein 8 protein FAF2 protein ETEA protein KIAA0887 protein UBXD8 protein UBXN3B protein

Information sourced from Uniprot.org