Human FABP6 protein (Recombinant) (N-His) (STJP007902)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FABP6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FABP6 |
| Gene ID | 2172 |
| Uniprot ID | FABP6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ala128 |
Additional Info
| Function | Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion. Isoform 2: Essential for the survival of colon cancer cells to bile acid-induced apoptosis. |
| Protein Name | GastrotropinGtFatty Acid-Binding Protein 6Ileal Lipid-Binding ProteinIlbpIntestinal 15 Kda ProteinI-15pIntestinal Bile Acid-Binding ProteinI-Babp |
| Database Links | Reactome: R-HSA-159418Reactome: R-HSA-163560Reactome: R-HSA-9623433 |
| Cellular Localisation | Isoform 1: CytoplasmMembranePeripheral Membrane ProteinCytoplasmic SideIsoform 2: CytoplasmLocalized Close To Nucleus On The Apical Side Of Both Normal And Neoplastic Cells |
| Alternative Protein Names | Gastrotropin proteinGt proteinFatty Acid-Binding Protein 6 proteinIleal Lipid-Binding Protein proteinIlbp proteinIntestinal 15 Kda Protein proteinI-15p proteinIntestinal Bile Acid-Binding Protein proteinI-Babp proteinFABP6 proteinILBP proteinILLBP protein |
Information sourced from Uniprot.org