Human ESRRG protein (Recombinant) (N-His) (STJP016018)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ESRRG-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | ESRRG |
| Gene ID | 2104 |
| Uniprot ID | ERR3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn235-Val458 |
Additional Info
| Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
| Function | Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Estrogen-Related Receptor Gamma proteinErr Gamma-2 proteinEstrogen Receptor-Related Protein 3 proteinNuclear Receptor Subfamily 3 Group B Member 3 proteinESRRG proteinERR3 proteinERRG2 proteinKIAA0832 proteinNR3B3 protein |
Information sourced from Uniprot.org