Human ERVK-6/HERV-K Env protein (Recombinant) (N-His) (STJP009290)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ERVK-6/HERV-K Env-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ERVK-6Uniprot ID=ENK6_HUMAN" |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu90-Thr632 |
Additional Info
| Post Translational Modifications | Specific enzymatic cleavages in vivo yield the mature SU and TM proteins. |
| Function | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties. SU mediates receptor recognition. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane. |
| Protein Name | Endogenous Retrovirus Group K Member 6 Env PolyproteinEnvk2 ProteinEnvelope PolyproteinHerv-K(C7 Envelope ProteinHerv-K(Hml-2.Hom Envelope ProteinHerv-K108 Envelope ProteinHerv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface ProteinSu - Transmembrane ProteinTm |
| Cellular Localisation | Transmembrane Protein: Cell MembraneSingle-Pass Type I Membrane ProteinSurface Protein: Cell MembranePeripheral Membrane ProteinThe Surface Protein Is Not Anchored To The MembraneBut Localizes To The Extracellular Surface Through Its Binding To TmEndogenous Retrovirus Group K Member 6 Env Polyprotein: Virion |
| Alternative Protein Names | Endogenous Retrovirus Group K Member 6 Env PolyproteinEnvk2 Protein proteinEnvelope PolyproteinHerv-K(C7 Envelope Protein proteinHerv-K(Hml-2.Hom Envelope Protein proteinHerv-K108 Envelope Protein proteinHerv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface Protein proteinSu - Transmembrane Protein proteinTm proteinERVK-6 proteinERVK6 protein |
Information sourced from Uniprot.org