SDS-PAGE gel of recombinant human Ephrin-A3 protein under reducing conditions stained with Coomassie blue

Human Ephrin-A3 protein (Recombinant) (His-Tag) (STJP018201)

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STJP018201
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Short Description :Recombinant-Human Ephrin-A3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:EFNA3
Gene ID:1944
Uniprot ID:EFNA3_HUMAN
Accession Number:NP_004943
Immunogen:Human
Immunogen Region:23-214aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMQGPGG ALGNRHAVYW NSSNQHLRRE GYTVQVNVND YLDIYCPHYN SSGVGPGAGP GPGGGAEQYV LYMVSRNGYR TCNASQGFKR WECNRPHAPH SPIKFSEKFQ RYSAFSLGYE FHAGHEYYYI STPTHNLHWK CLRMKVFVCC ASTSHSGEKP VPTLPQFTMG PNVKINVLED FEGENPQVPK LEKSISG
Tissue Specificity Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Protein Name Ephrin-A3
Efl-2
Ehk1 Ligand
Ehk1-L
Eph-Related Receptor Tyrosine Kinase Ligand 3
Lerk-3
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928663
Reactome: R-HSA-3928665
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Ephrin-A3 protein
Efl-2 protein
Ehk1 Ligand protein
Ehk1-L protein
Eph-Related Receptor Tyrosine Kinase Ligand 3 protein
Lerk-3 protein
EFNA3 protein
EFL2 protein
EPLG3 protein
LERK3 protein

Information sourced from Uniprot.org

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